ignm.ccbb pitt.edu

iGNM - Online service for Gaussian Network Model

Computational and Systems Biology. What is the GNM DB? Which questions can be answered? Several studies in the last decade have drawn attention to the significance of intrinsic dynamics as a major determinant of the mechanism of action of proteins and their complexes 1-5. Intrinsic dynamics refers to conformational changes intrinsically favored by 3D structure, which often underlie the adaptation of biomolecules to functional interactions 6. Or which ones provide adequate flexibility. 2 Dobbins,S46.

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iGNM - Online service for Gaussian Network Model

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Computational and Systems Biology. What is the GNM DB? Which questions can be answered? Several studies in the last decade have drawn attention to the significance of intrinsic dynamics as a major determinant of the mechanism of action of proteins and their complexes 1-5. Intrinsic dynamics refers to conformational changes intrinsically favored by 3D structure, which often underlie the adaptation of biomolecules to functional interactions 6. Or which ones provide adequate flexibility. 2 Dobbins,S46.

PARSED CONTENT

The web site ignm.ccbb.pitt.edu states the following, "What is the GNM DB? Which questions can be answered? Several studies in the last decade have drawn attention to the significance of intrinsic dynamics as a major determinant of the mechanism of action of proteins and their complexes 1-5." We noticed that the website said " Intrinsic dynamics refers to conformational changes intrinsically favored by 3D structure, which often underlie the adaptation of biomolecules to functional interactions 6." It also said " Or which ones provide adequate flexibility."

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