gnmdb.csb pitt.edu

iGNM - Online service for Gaussian Network Model

Computational and Systems Biology. What is the GNM DB? Which questions can be answered? Several studies in the last decade have drawn attention to the significance of intrinsic dynamics as a major determinant of the mechanism of action of proteins and their complexes 1-5. Intrinsic dynamics refers to conformational changes intrinsically favored by 3D structure, which often underlie the adaptation of biomolecules to functional interactions 6. Or which ones provide adequate flexibility. 2 Dobbins,S46.

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NIHBTR Collaboration Through Dissemination

Biomedical Technology Resources create critical, often unique technology and methods at the forefront of their respective fields, and apply them to a broad range of basic, translational, and clinical research. This is accomplished through a synergistic interaction of technical and biomedical expertise, both within the resources and through intensive collaborations with other leading laboratories.

Dynomics Portal 1.0 - Dynamics Proteomics and Beyond

At the core of o.

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iGNM - Online service for Gaussian Network Model

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Computational and Systems Biology. What is the GNM DB? Which questions can be answered? Several studies in the last decade have drawn attention to the significance of intrinsic dynamics as a major determinant of the mechanism of action of proteins and their complexes 1-5. Intrinsic dynamics refers to conformational changes intrinsically favored by 3D structure, which often underlie the adaptation of biomolecules to functional interactions 6. Or which ones provide adequate flexibility. 2 Dobbins,S46.

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The web site gnmdb.csb.pitt.edu states the following, "What is the GNM DB? Which questions can be answered? Several studies in the last decade have drawn attention to the significance of intrinsic dynamics as a major determinant of the mechanism of action of proteins and their complexes 1-5." We noticed that the website said " Intrinsic dynamics refers to conformational changes intrinsically favored by 3D structure, which often underlie the adaptation of biomolecules to functional interactions 6." It also said " Or which ones provide adequate flexibility."

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